Search on: TRANSFORMING GROWTH FACTORS 
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Descriptor English:   Transforming Growth Factors 
Descriptor Spanish:   Factores de Crecimiento Transformadores 
Descriptor Portuguese:   Fatores de Crescimento Transformadores 
Synonyms English:   Transforming Growth Factor
Factor, Transforming Growth
Factors, Transforming Growth
Growth Factor, Transforming
Growth Factors, Transforming  
Tree Number:   D12.644.276.963
D12.776.467.960
D23.529.960
Definition English:   Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA. 
Indexing Annotation English:   general or unspecified; prefer specifics
History Note English:   89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   23851 
Unique Identifier:   D015291 

Occurrence in VHL:
 

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